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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GDF9
All Species:
2.42
Human Site:
S226
Identified Species:
4.85
UniProt:
O60383
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60383
NP_005251.1
454
51444
S226
L
L
Q
P
L
V
A
S
N
K
R
S
I
H
M
Chimpanzee
Pan troglodytes
XP_527008
455
51476
N227
L
Q
P
L
V
A
S
N
K
R
S
I
H
M
S
Rhesus Macaque
Macaca mulatta
XP_001101902
271
31418
E48
G
S
H
S
Q
Q
L
E
L
W
G
I
L
P
S
Dog
Lupus familis
XP_549005
393
44984
S170
F
P
S
S
G
R
G
S
S
N
P
S
L
M
S
Cat
Felis silvestris
Mouse
Mus musculus
Q07105
441
49630
P215
D
V
T
S
L
L
Q
P
L
V
T
S
S
E
R
Rat
Rattus norvegicus
P49001
393
44364
I170
S
F
Q
H
R
I
N
I
Y
E
I
I
K
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510645
359
41050
L136
R
K
S
D
T
Q
F
L
C
Q
M
K
S
R
I
Chicken
Gallus gallus
Q90752
405
46039
I182
R
G
F
H
R
I
N
I
Y
E
V
M
K
P
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
P85857
404
46271
L181
L
A
S
R
S
I
D
L
Q
D
S
R
K
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07713
588
65849
R345
R
S
S
A
N
R
T
R
Y
Q
V
L
V
Y
D
Honey Bee
Apis mellifera
XP_001122815
374
42068
Y150
K
L
G
R
I
L
I
Y
D
I
L
R
P
G
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P48970
395
43818
N172
L
E
S
R
T
R
L
N
S
I
V
S
L
K
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
50
28.6
N.A.
72
21.5
N.A.
26.4
21.8
N.A.
21.1
N.A.
21.7
21.3
N.A.
20.2
Protein Similarity:
100
99.1
54.1
45.1
N.A.
80.6
39.2
N.A.
44.2
38.3
N.A.
39.6
N.A.
36.9
40.3
N.A.
39.4
P-Site Identity:
100
6.6
0
13.3
N.A.
13.3
6.6
N.A.
0
0
N.A.
6.6
N.A.
0
6.6
N.A.
13.3
P-Site Similarity:
100
33.3
6.6
26.6
N.A.
26.6
20
N.A.
13.3
20
N.A.
13.3
N.A.
20
26.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
9
0
9
9
0
0
0
0
0
0
9
17
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
9
0
0
9
0
0
9
0
9
9
0
0
0
0
17
% D
% Glu:
0
9
0
0
0
0
0
9
0
17
0
0
0
9
9
% E
% Phe:
9
9
9
0
0
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
9
9
9
0
9
0
9
0
0
0
9
0
0
9
0
% G
% His:
0
0
9
17
0
0
0
0
0
0
0
0
9
9
0
% H
% Ile:
0
0
0
0
9
25
9
17
0
17
9
25
9
0
9
% I
% Lys:
9
9
0
0
0
0
0
0
9
9
0
9
25
9
0
% K
% Leu:
34
17
0
9
17
17
17
17
17
0
9
9
25
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
9
0
17
9
% M
% Asn:
0
0
0
0
9
0
17
17
9
9
0
0
0
0
0
% N
% Pro:
0
9
9
9
0
0
0
9
0
0
9
0
9
25
0
% P
% Gln:
0
9
17
0
9
17
9
0
9
17
0
0
0
0
0
% Q
% Arg:
25
0
0
25
17
25
0
9
0
9
9
17
0
9
9
% R
% Ser:
9
17
42
25
9
0
9
17
17
0
17
34
17
0
25
% S
% Thr:
0
0
9
0
17
0
9
0
0
0
9
0
0
0
0
% T
% Val:
0
9
0
0
9
9
0
0
0
9
25
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
25
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _